The small company won first place at the 17th Annual World Congress on Insulin Resistance, Diabetes and Cardiovascular Diseases in December. This is what we are doing,” he said.Ĭoncenter BioPharma has already received recognition. More than 150 companies are developing diagnostics or applications for diabetes, but there are no drugs to treat the actual problem of insulin resistance without side effects. “The estimated cost of treating diabetes per year is over $850 billion.
The company is currently raising $5 million to fund this year’s tests on the drug. The study by researchers at Linköping University in Sweden has been published in the scientific journal New England Journal of Medicine. We are currently raising funds to do all of that,” Chevion told ISRAEL21c. A small pilot study in which researchers attempted to slow attacks mounted by the immune system on insulin-producing cells in type 1 diabetes has given promising results. Then we will submit another IND (Investigational New Drug) application to go to phase 2b, by the end of 2020. We plan to perform clinical studies here in Israel. “We are working on accommodating those requests and making the final formulation of the drug as a pill.
ISRAEL TYPE 1 DIABETES PILOT SERIES
The FDA has already approved clinical trials after the company completes a series of pre-clinical toxicology studies on the drug. Now, the company is working to get the new drug approved by the United States Food and Drug Administration. When researchers tested Zygosid-50 on animals, it was able to restore insulin sensitivity by more than 90%, lowered glucose, and suppressed high inflammation levels within the body.Ĭhevion explained that the drug had no bad side effects on animals.
ISRAEL TYPE 1 DIABETES PILOT FREE
“On the molecular level, Zygosid-50 is a potent anti-inflammatory drug that forces an intra-cellular exchange – removal of ‘bad’ free iron with zinc, depositing the zinc ion within the cells.” “Zygosids work by robustly reducing insulin resistance and normalizing all diabetes-associated parameters to the normal range,” the professor told ISRAEL21c.
For the primary outcome, only individuals classified as type 2 diabetes were included. Mottie (Mordechai) Chevion developed the drug at Hebrew University-Hadassah Medical Center in Jerusalem. The INDR classifies type 1, type 2, and uncertain types of diabetes, according to purchases of glucose lowering medications, as reported previously (10, 11) (all supplementary material and figures are located in a digital research materials repository). Type 2 diabetes occurs when the body is no longer sensitive to insulin or the pancreas does not make enough.Ĭoncenter Biopharma cofounder and CSO Prof. Insulin is the hormone that keeps your blood sugar from getting too high after you eat.
JERUSALEM, Israel – An Israeli company based in Jerusalem is developing a drug that could change the lives of countless people suffering from Type 2 diabetes.Ĭoncenter BioPharma created a new non-steroidal anti-inflammatory drug called Zygosid-50 that targets the disease at its source by restoring the body’s sensitivity to insulin.
0 kommentar(er)
